Age-dependent differences in microglial responses to systemic inflammation are evident as early as middle age
نویسندگان
چکیده
منابع مشابه
Age-dependent differences in microglial responses to systemic inflammation are evident as early as middle age.
Whereas age increases microglial inflammatory activities and impairs their ability to effectively regulate their immune response, it is unclear at what age these exaggerated responses begin. We tested the hypotheses that augmented microglial responses to inflammatory challenge are present as early as middle age and that repeated stimulation of primed microglia in vivo would reveal microglial se...
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ژورنال
عنوان ژورنال: Physiological Genomics
سال: 2016
ISSN: 1094-8341,1531-2267
DOI: 10.1152/physiolgenomics.00129.2015